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Survivin Improves Reprogramming Efficiency of Human Neural Progenitors by Single Molecule OCT4

Induced pluripotent stem (iPS) cells have been generated from human somatic cells by ectopic expression of four Yamanaka factors. Here, we report that Survivin, an apoptosis inhibitor, can enhance iPS cells generation from human neural progenitor cells (NPCs) together with one factor OCT4 (1F-OCT4-S...

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Detalles Bibliográficos
Autores principales: Zhou, Shixin, Liu, Yinan, Feng, Ruopeng, Wang, Caiyun, Jiang, Sibo, Zhang, Xiaoyan, Lan, Feng, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128714/
https://www.ncbi.nlm.nih.gov/pubmed/27974895
http://dx.doi.org/10.1155/2016/4729535