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A computationally efficient algorithm for fitting ion channel parameters
Continuous time Markov models have been widely used to describe ion channel kinetics, providing explicit representation of channel states and transitions. Fitting models to experimental data remains a computationally demanding task largely due to the high cost of model evaluation. Here, we propose a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128735/ https://www.ncbi.nlm.nih.gov/pubmed/27924282 http://dx.doi.org/10.1016/j.mex.2016.11.001 |