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Chiral Alkyl Halides: Underexplored Motifs in Medicine

While alkyl halides are valuable intermediates in synthetic organic chemistry, their use as bioactive motifs in drug discovery and medicinal chemistry is rare in comparison. This is likely attributable to the common misconception that these compounds are merely non-specific alkylators in biological...

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Detalles Bibliográficos
Autores principales: Gál, Bálint, Bucher, Cyril, Burns, Noah Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128749/
https://www.ncbi.nlm.nih.gov/pubmed/27827902
http://dx.doi.org/10.3390/md14110206