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Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42

The generation of cell polarity is essential for the development of multi-cellular organisms as well as for the function of epithelial organs in the mature animal. Small GTPases regulate the establishment and maintenance of polarity through effects on cytoskeleton, membrane trafficking, and signalin...

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Detalles Bibliográficos
Autores principales: Lu, Ruifeng, Wilson, Jean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128791/
https://www.ncbi.nlm.nih.gov/pubmed/27901125
http://dx.doi.org/10.1038/srep38249