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Membrane Core-Specific Antimicrobial Action of Cathelicidin LL-37 Peptide Switches Between Pore and Nanofibre Formation

Membrane-disrupting antimicrobial peptides provide broad-spectrum defence against localized bacterial invasion in a range of hosts including humans. The most generally held consensus is that targeting to pathogens is based on interactions with the head groups of membrane lipids. Here we show that th...

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Detalles Bibliográficos
Autores principales: Shahmiri, Mahdi, Enciso, Marta, Adda, Christopher G., Smith, Brian J., Perugini, Matthew A., Mechler, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128859/
https://www.ncbi.nlm.nih.gov/pubmed/27901075
http://dx.doi.org/10.1038/srep38184