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Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation

Resveratrol is a natural compound found in red wine that has been suggested to exert its potential health benefit through the activation of SIRT1, a crucial member of the mammalian NAD(+)-dependent deacetylases. SIRT1 has emerged as an attractive therapeutic target for many aging related diseases, h...

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Detalles Bibliográficos
Autores principales: Hou, Xuben, Rooklin, David, Fang, Hao, Zhang, Yingkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128864/
https://www.ncbi.nlm.nih.gov/pubmed/27901083
http://dx.doi.org/10.1038/srep38186