NMR Crystallography of a Carbanionic Intermediate in Tryptophan Synthase: Chemical Structure, Tautomerization, and Reaction Specificity

[Image: see text] Carbanionic intermediates play a central role in the catalytic transformations of amino acids performed by pyridoxal-5′-phosphate (PLP)-dependent enzymes. Here, we make use of NMR crystallography—the synergistic combination of solid-state nuclear magnetic resonance, X-ray crystallo...

Descripción completa

Detalles Bibliográficos
Autores principales: Caulkins, Bethany G., Young, Robert P., Kudla, Ryan A., Yang, Chen, Bittbauer, Thomas J., Bastin, Baback, Hilario, Eduardo, Fan, Li, Marsella, Michael J., Dunn, Michael F., Mueller, Leonard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129030/
https://www.ncbi.nlm.nih.gov/pubmed/27779384
http://dx.doi.org/10.1021/jacs.6b08937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129030/
https://www.ncbi.nlm.nih.gov/pubmed/27779384
http://dx.doi.org/10.1021/jacs.6b08937

Ejemplares similares