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p53 signaling modulation of cell cycle arrest and viral replication in porcine circovirus type 2 infection cells

Porcine circovirus type 2 (PCV2) is a ubiquitous pathogen in the swine industry worldwide. Previous studies have shown that PCV2 infection induces host cell apoptosis through up-regulation of p53. To further identify the regulatory roles of p53 signaling in the process of PCV2 infection, we establis...

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Detalles Bibliográficos
Autores principales: Xu, Dan, Du, Qian, Han, Cong, Wang, Zengguo, Zhang, Xiujuan, Wang, Tongtong, Zhao, Xiaomin, Huang, Yong, Tong, Dewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129207/
https://www.ncbi.nlm.nih.gov/pubmed/27899159
http://dx.doi.org/10.1186/s13567-016-0403-4