Lymphocyte Kv1.3-channels in the pathogenesis of chronic obstructive pulmonary disease: novel therapeutic implications of targeting the channels by commonly used drugs

In patients with chronic obstructive pulmonary disease (COPD), over-activated T-lymphocytes produce pro-inflammatory cytokines and proliferate in situ in the lower airways and pulmonary parenchyma, contributing substantially to the pathogenesis of the disease. Despite our understanding of the molecu...

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Detalles Bibliográficos
Autores principales: Kazama, Itsuro, Tamada, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129211/
https://www.ncbi.nlm.nih.gov/pubmed/27956907
http://dx.doi.org/10.1186/s13223-016-0168-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129211/
https://www.ncbi.nlm.nih.gov/pubmed/27956907
http://dx.doi.org/10.1186/s13223-016-0168-3

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