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Selective Enzymatic Transformation to Aldehydes in vivo by Fungal Carboxylate Reductase from Neurospora crassa

The enzymatic reduction of carboxylic acids is in its infancy with only a handful of biocatalysts available to this end. We have increased the spectrum of carboxylate‐reducing enzymes (CARs) with the sequence of a fungal CAR from Neurospora crassa OR74A (NcCAR). NcCAR was efficiently expressed in E....

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Detalles Bibliográficos
Autores principales: Schwendenwein, Daniel, Fiume, Giuseppe, Weber, Hansjörg, Rudroff, Florian, Winkler, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129534/
https://www.ncbi.nlm.nih.gov/pubmed/27917101
http://dx.doi.org/10.1002/adsc.201600914