ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons

ST8SIA2 is a polysialyltransferase that attaches polysialic acid to the glycoproteins NCAM1 and CADM1. Polysialylation is involved in brain development and plasticity. ST8SIA2 is a schizophrenia candidate gene, and St8sia2 (−/−) mice exhibit schizophrenia‐like behavior. We sought to identify new pat...

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Detalles Bibliográficos
Autores principales: Szewczyk, Lukasz Mateusz, Brozko, Nikola, Nagalski, Andrzej, Röckle, Iris, Werneburg, Sebastian, Hildebrandt, Herbert, Wisniewska, Marta Barbara, Kuznicki, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129544/
https://www.ncbi.nlm.nih.gov/pubmed/27534376
http://dx.doi.org/10.1002/glia.23048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129544/
https://www.ncbi.nlm.nih.gov/pubmed/27534376
http://dx.doi.org/10.1002/glia.23048

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