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The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin‐like protease(s) in a subpopulation of microglia in neonatal rat brain

To differentiate subtypes of microglia (MG), we developed a novel monoclonal antibody, 9F5, against one subtype (type 1) of rat primary MG. The 9F5 showed high selectivity for this cell type in Western blot and immunocytochemical analyses and no cross‐reaction with rat peritoneal macrophages (Mφ). W...

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Detalles Bibliográficos
Autores principales: Kawahara, Kohichi, Hirata, Hiroshi, Ohbuchi, Kengo, Nishi, Kentaro, Maeda, Akira, Kuniyasu, Akihiko, Yamada, Daisuke, Maeda, Takehiko, Tsuji, Akihiko, Sawada, Makoto, Nakayama, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129557/
https://www.ncbi.nlm.nih.gov/pubmed/27464357
http://dx.doi.org/10.1002/glia.23034