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The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin‐like protease(s) in a subpopulation of microglia in neonatal rat brain
To differentiate subtypes of microglia (MG), we developed a novel monoclonal antibody, 9F5, against one subtype (type 1) of rat primary MG. The 9F5 showed high selectivity for this cell type in Western blot and immunocytochemical analyses and no cross‐reaction with rat peritoneal macrophages (Mφ). W...
Autores principales: | Kawahara, Kohichi, Hirata, Hiroshi, Ohbuchi, Kengo, Nishi, Kentaro, Maeda, Akira, Kuniyasu, Akihiko, Yamada, Daisuke, Maeda, Takehiko, Tsuji, Akihiko, Sawada, Makoto, Nakayama, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129557/ https://www.ncbi.nlm.nih.gov/pubmed/27464357 http://dx.doi.org/10.1002/glia.23034 |
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