Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell‐type‐specific

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder that is caused by a CAG expansion in the Huntingtin (HTT) gene, leading to HTT inclusion formation in the brain. The mutant huntingtin protein (mHTT) is ubiquitously expressed and therefore nuclear inclusion...

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Detalles Bibliográficos
Autores principales: Jansen, Anne H.P., van Hal, Maurik, op den Kelder, Ilse C., Meier, Romy T., de Ruiter, Anna‐Aster, Schut, Menno H., Smith, Donna L., Grit, Corien, Brouwer, Nieske, Kamphuis, Willem, Boddeke, H.W.G.M., den Dunnen, Wilfred F.A., van Roon, Willeke M.C., Bates, Gillian P., Hol, Elly M., Reits, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129569/
https://www.ncbi.nlm.nih.gov/pubmed/27615381
http://dx.doi.org/10.1002/glia.23050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129569/
https://www.ncbi.nlm.nih.gov/pubmed/27615381
http://dx.doi.org/10.1002/glia.23050

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