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Accumulation of intestinal tissue 3-deoxyglucosone attenuated GLP-1 secretion and its insulinotropic effect in rats

BACKGROUND: Our recent findings support the idea that 3-deoxyglucosone (3DG), a dietary composition, has been suggested as an independent factor for the development of prediabetes. Secretion of glucagon-like peptide-1 (GLP-1) has been suggested to be impaired in T2DM and in conditions associated wit...

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Detalles Bibliográficos
Autores principales: Zhang, Lurong, Song, Xiudao, Zhou, Liang, Liang, Guoqiang, Xu, Heng, Wang, Fei, Huang, Fei, Jiang, Guorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129672/
https://www.ncbi.nlm.nih.gov/pubmed/27956941
http://dx.doi.org/10.1186/s13098-016-0194-9