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Iroquois homeobox transcription factor (Irx5) promotes G(1)/S-phase transition in vascular smooth muscle cells by CDK2-dependent activation
The Iroquois homeobox (Irx5) gene is essential in embryonic development and cardiac electrophysiology. Although recent studies have reported that IRX5 protein is involved in regulation of the cell cycle and apoptosis in prostate cancer cells, little is known about the role of IRX5 in the adult vascu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129766/ https://www.ncbi.nlm.nih.gov/pubmed/27170637 http://dx.doi.org/10.1152/ajpcell.00293.2015 |