De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas

About 20% hepatocellular carcinomas (HCCs) display wild-type β-catenin, enhanced Wnt signaling, hepatocyte dedifferentiation and bad outcome, suggesting a specific impact of Wnt signals on HCC stem/progenitor cells. To study Wnt-specific molecular pathways, cell fates and clinical outcome, we fine-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Mebarki, Sihem, Désert, Romain, Sulpice, Laurent, Sicard, Marie, Desille, Mireille, Canal, Frédéric, Schneider, Hélène Dubois-Pot, Bergeat, Damien, Turlin, Bruno, Bellaud, Pascale, Lavergne, Elise, Guével, Rémy Le, Corlu, Anne, Perret, Christine, Coulouarn, Cédric, Clément, Bruno, Musso, Orlando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129911/
https://www.ncbi.nlm.nih.gov/pubmed/27191501
http://dx.doi.org/10.18632/oncotarget.9346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129911/
https://www.ncbi.nlm.nih.gov/pubmed/27191501
http://dx.doi.org/10.18632/oncotarget.9346

Ejemplares similares