Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells

Exposure to estrogen has long been associated with an increased risk of developing breast cancer. However, how estrogen signaling promotes breast carcinogenesis remains elusive. Senescence is known as an important protective response to oncogenic events. We aimed to elucidate the role of estrogen re...

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Detalles Bibliográficos
Autores principales: Liu, Zhao, Wang, Long, Yang, Junhua, Bandyopadhyay, Abhik, Kaklamani, Virginia, Wang, Shui, Sun, Lu-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129916/
https://www.ncbi.nlm.nih.gov/pubmed/27259243
http://dx.doi.org/10.18632/oncotarget.9772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129916/
https://www.ncbi.nlm.nih.gov/pubmed/27259243
http://dx.doi.org/10.18632/oncotarget.9772

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