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Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer's disease

Stress has been implicated as a risk factor for the severity and progression of sporadic Alzheimer's disease (AD). Early life experiences determine stress responsivity in later life, and modulate age-dependent cognitive decline. Therefore, we examined whether early life experiences influence AD...

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Detalles Bibliográficos
Autores principales: Lesuis, Sylvie L., Maurin, Herve, Borghgraef, Peter, Lucassen, Paul J., Leuven, Fred Van, Krugers, Harm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129918/
https://www.ncbi.nlm.nih.gov/pubmed/27259247
http://dx.doi.org/10.18632/oncotarget.9776