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Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer's disease
Stress has been implicated as a risk factor for the severity and progression of sporadic Alzheimer's disease (AD). Early life experiences determine stress responsivity in later life, and modulate age-dependent cognitive decline. Therefore, we examined whether early life experiences influence AD...
Autores principales: | Lesuis, Sylvie L., Maurin, Herve, Borghgraef, Peter, Lucassen, Paul J., Leuven, Fred Van, Krugers, Harm J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129918/ https://www.ncbi.nlm.nih.gov/pubmed/27259247 http://dx.doi.org/10.18632/oncotarget.9776 |
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