Transient enhancement of proliferation of neural progenitors and impairment of their long-term survival in p25 transgenic mice

Cyclin-dependent kinase 5 (CDK5) regulates important neuronal functions via p35. p35 undergoes cleavage in response to neuronal activity and neurotoxic conditions to release its subunit p25. Although p25 has been implicated in various neurodegenerative diseases, the mechanisms by which p25 mediates...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Donghua, Zhou, Yijing, Liu, Long, Dong, Fengping, Shu, Tianzhi, Zhou, Ying, Tsai, Li-Huei, Mao, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129921/
https://www.ncbi.nlm.nih.gov/pubmed/27283769
http://dx.doi.org/10.18632/oncotarget.9834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129921/
https://www.ncbi.nlm.nih.gov/pubmed/27283769
http://dx.doi.org/10.18632/oncotarget.9834

Ejemplares similares