Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes

Our previous genome-wide association studies showed that DNA methyltransferase 1 (DNMT1) is associated with increased susceptibility to type 2 diabetes (T2D) in Han Chinese individuals. Here, we aimed to further evaluate the role of DNMT1 in T2D. We performed a genome-wide DNA methylation array and...

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Detalles Bibliográficos
Autores principales: Chen, Yng-Tay, Liao, Jiunn-Wang, Tsai, Ya-Ching, Tsai, Fuu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129922/
https://www.ncbi.nlm.nih.gov/pubmed/27322146
http://dx.doi.org/10.18632/oncotarget.10043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129922/
https://www.ncbi.nlm.nih.gov/pubmed/27322146
http://dx.doi.org/10.18632/oncotarget.10043

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