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Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes
Our previous genome-wide association studies showed that DNA methyltransferase 1 (DNMT1) is associated with increased susceptibility to type 2 diabetes (T2D) in Han Chinese individuals. Here, we aimed to further evaluate the role of DNMT1 in T2D. We performed a genome-wide DNA methylation array and...
Autores principales: | Chen, Yng-Tay, Liao, Jiunn-Wang, Tsai, Ya-Ching, Tsai, Fuu-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129922/ https://www.ncbi.nlm.nih.gov/pubmed/27322146 http://dx.doi.org/10.18632/oncotarget.10043 |
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