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TSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes

Elevated thyroid-stimulating hormone (TSH) levels often accompany impaired LV diastolic function and subtle systolic dysfunction in subclinical hypothyroidism (sHT). These cardiac dysfunctions are characterized by increases in mean aortic acceleration and pre-ejection/ejection time ratios. To explor...

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Detalles Bibliográficos
Autores principales: Dong, Jiajia, Gao, Cuixia, Liu, Jing, Cao, Yunshan, Tian, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129926/
https://www.ncbi.nlm.nih.gov/pubmed/27206677
http://dx.doi.org/10.18632/oncotarget.9393