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TSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes
Elevated thyroid-stimulating hormone (TSH) levels often accompany impaired LV diastolic function and subtle systolic dysfunction in subclinical hypothyroidism (sHT). These cardiac dysfunctions are characterized by increases in mean aortic acceleration and pre-ejection/ejection time ratios. To explor...
Autores principales: | Dong, Jiajia, Gao, Cuixia, Liu, Jing, Cao, Yunshan, Tian, Limin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129926/ https://www.ncbi.nlm.nih.gov/pubmed/27206677 http://dx.doi.org/10.18632/oncotarget.9393 |
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