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Activation of volume-sensitive Cl(−) channel mediates autophagy-related cell death in myocardial ischaemia/reperfusion injury

Excessive reactive oxygen species (ROS) plays an important role in myocardial ischemia/reperfusion (I/R) injury, which triggers not only myocardial cellular apoptosis but also autophagy-related cell death, in which volume-sensitive outwardly rectifying (VSOR) Cl(−) channel-activated by ROS contribut...

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Detalles Bibliográficos
Autores principales: Xia, Yuesheng, Liu, Yan, Xia, Tong, Li, Xing, Huo, Cong, Jia, Xin, Wang, Lin, Xu, Rong, Wang, Ning, Zhang, Mingming, Li, Hong, Wang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129937/
https://www.ncbi.nlm.nih.gov/pubmed/27322431
http://dx.doi.org/10.18632/oncotarget.10050