Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence

Immunologically naïve lymphocytes are kept in a quiescent state until antigen engagement. These quiescent immune cells are characterized by small cell size, lack of spontaneous proliferation and low metabolic rate. Lymphocyte quiescence is actively enforced condition which ensures the preservation o...

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Detalles Bibliográficos
Autores principales: Omar, Ibrahim, Lapenna, Antonio, Cohen-Daniel, Leonor, Tirosh, Boaz, Berger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129940/
https://www.ncbi.nlm.nih.gov/pubmed/27276683
http://dx.doi.org/10.18632/oncotarget.9818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129940/
https://www.ncbi.nlm.nih.gov/pubmed/27276683
http://dx.doi.org/10.18632/oncotarget.9818

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