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Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence
Immunologically naïve lymphocytes are kept in a quiescent state until antigen engagement. These quiescent immune cells are characterized by small cell size, lack of spontaneous proliferation and low metabolic rate. Lymphocyte quiescence is actively enforced condition which ensures the preservation o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129940/ https://www.ncbi.nlm.nih.gov/pubmed/27276683 http://dx.doi.org/10.18632/oncotarget.9818 |