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5d, a novel analogue of 3-n-butylphthalide, decreases NADPH oxidase activity through the positive regulation of CK2 after ischemia/reperfusion injury

5d, a novel analogue of the racemic 3-n-butylphthalide (NBP), has been reported for its free radical scavenging activity in vitro and preventive neuroprotection in vivo. Nevertheless, the mechanism by which 5d attenuated ischemia/reperfusion (I/R) injury is still unknown. Our results showed that 5d...

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Detalles Bibliográficos
Autores principales: Zhou, Jia, Zhang, Yi-hua, Song, Hui-zhu, Ji, Hui, Wang, Xiao-li, Wang, Lei, Qian, Jun, Ling, Jing-jing, Ping, Feng-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129944/
https://www.ncbi.nlm.nih.gov/pubmed/27276705
http://dx.doi.org/10.18632/oncotarget.8548