Heparanase expression upregulates platelet adhesion activity and thrombogenicity

Heparanase is an endo-glucuronidase that specifically cleaves heparan sulfate (HS) and heparin polysaccharides. The enzyme is expressed at low levels in normal tissues, but is often upregulated under pathological conditions such as cancer and inflammation. Normal human platelets express exceptionall...

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Detalles Bibliográficos
Autores principales: Cui, Hao, Tan, Ying-xia, Österholm, Cecilia, Zhang, Xiao, Hedin, Ulf, Vlodavsky, Israel, Li, Jin-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129947/
https://www.ncbi.nlm.nih.gov/pubmed/27129145
http://dx.doi.org/10.18632/oncotarget.8960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129947/
https://www.ncbi.nlm.nih.gov/pubmed/27129145
http://dx.doi.org/10.18632/oncotarget.8960

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