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miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1

MicroRNAs play important roles in the pathogenesis of cancers by inhibiting gene expression at posttranscriptional level. Here, we identified that miR-590 and its predicted target gene RB1 are differentially expressed in T-cell acute lymphoblastic leukaemia (T-ALL). The correlation between miR-590 a...

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Detalles Bibliográficos
Autores principales: Miao, Mei-hua, Ji, Xue-qiang, Zhang, Hao, Xu, Jun, Zhu, Hong, Shao, Xue-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129950/
https://www.ncbi.nlm.nih.gov/pubmed/27036041
http://dx.doi.org/10.18632/oncotarget.8414