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Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer

Autophagy is a cellular degrading process that promotes tumor cell survival or cell death in cancer, depending on the progress of oncogenesis. Protein light chain 3 (LC3) and p62/SQSTM1 (p62) are associated with autophagosomal membranes that engulf cytoplasmic content for subsequent degradation. We...

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Detalles Bibliográficos
Autores principales: Schläfli, Anna M., Adams, Olivia, Galván, José A., Gugger, Mathias, Savic, Spasenija, Bubendorf, Lukas, Schmid, Ralph A., Becker, Karl-Friedrich, Tschan, Mario P., Langer, Rupert, Berezowska, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129952/
https://www.ncbi.nlm.nih.gov/pubmed/27250032
http://dx.doi.org/10.18632/oncotarget.9647