Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance

Lysine demethylase 5A (KDM5A/RBP2/JARID1A) is a histone lysine demethylase that is overexpressed in several human cancers including lung, gastric, breast and liver cancers. It plays key roles in important cancer processes including tumorigenesis, metastasis, and drug tolerance, making it a potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Gale, Molly, Sayegh, Joyce, Cao, Jian, Norcia, Michael, Gareiss, Peter, Hoyer, Denton, Merkel, Jane S., Yan, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129982/
https://www.ncbi.nlm.nih.gov/pubmed/27224921
http://dx.doi.org/10.18632/oncotarget.9539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129982/
https://www.ncbi.nlm.nih.gov/pubmed/27224921
http://dx.doi.org/10.18632/oncotarget.9539

Ejemplares similares