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Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis
The MUC1 glycoprotein is overexpressed and aberrantly glycosylated in >90% of pancreatic ductal adenocarcinoma cases and impacts tumor progression by initiating downstream signaling through phosphorylation of its cytoplasmic tail. Previous studies have demonstrated that MUC1 alters expression of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129987/ https://www.ncbi.nlm.nih.gov/pubmed/27220889 http://dx.doi.org/10.18632/oncotarget.9557 |