Cargando…

Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis

The MUC1 glycoprotein is overexpressed and aberrantly glycosylated in >90% of pancreatic ductal adenocarcinoma cases and impacts tumor progression by initiating downstream signaling through phosphorylation of its cytoplasmic tail. Previous studies have demonstrated that MUC1 alters expression of...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanson, Ryan L., Brown, Roger B., Steele, Maria M., Grandgenett, Paul M., Grunkemeyer, James A., Hollingsworth, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129987/
https://www.ncbi.nlm.nih.gov/pubmed/27220889
http://dx.doi.org/10.18632/oncotarget.9557