Cargando…
Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis
The MUC1 glycoprotein is overexpressed and aberrantly glycosylated in >90% of pancreatic ductal adenocarcinoma cases and impacts tumor progression by initiating downstream signaling through phosphorylation of its cytoplasmic tail. Previous studies have demonstrated that MUC1 alters expression of...
Autores principales: | Hanson, Ryan L., Brown, Roger B., Steele, Maria M., Grandgenett, Paul M., Grunkemeyer, James A., Hollingsworth, Michael A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129987/ https://www.ncbi.nlm.nih.gov/pubmed/27220889 http://dx.doi.org/10.18632/oncotarget.9557 |
Ejemplares similares
-
MicroRNA-200c Modulates the Expression of MUC4 and MUC16 by Directly Targeting Their Coding Sequences in Human Pancreatic Cancer
por: Radhakrishnan, Prakash, et al.
Publicado: (2013) -
Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)
por: Hanson, Ryan L., et al.
Publicado: (2016) -
The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF
por: Behrens, Michelle E., et al.
Publicado: (2010) -
Xanthohumol targets the ERK1/2-Fra1 signaling axis to reduce cyclin D1 expression and inhibit non-small cell lung cancer
por: Gao, Feng, et al.
Publicado: (2020) -
To FRA or not to FRA: What is the question for science education?
por: Dagher, Zoubeida R., et al.
Publicado: (2023)