Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling

High-risk type II endometrial cancers account for ~30% of cases but ~75% of deaths due, in part, to their tendency to metastasize. Histopathological studies of type II endometrial cancers (non-endometrioid, mostly serous) suggest overproduction of activin B and down-regulation of E-cadherin, both of...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Siyuan, Klausen, Christian, Cheng, Jung-Chien, Leung, Peter C.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129992/
https://www.ncbi.nlm.nih.gov/pubmed/27223076
http://dx.doi.org/10.18632/oncotarget.9483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129992/
https://www.ncbi.nlm.nih.gov/pubmed/27223076
http://dx.doi.org/10.18632/oncotarget.9483

Ejemplares similares