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JARID2 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition through PTEN/AKT signaling

JARID2 is crucial for maintenance of pluripotency and differentiation of embryonic stem cells. However, little is known about the role of JARID2 in metastasis of hepatocellular carcinoma (HCC). This study found that JARID2 expression was significantly higher in HCC tissues than that in adjacent non-...

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Detalles Bibliográficos
Autores principales: Lei, Xiong, Xu, Jiang-Feng, Chang, Rui-Min, Fang, Feng, Zuo, Chao-Hui, Yang, Lian-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130007/
https://www.ncbi.nlm.nih.gov/pubmed/27259236
http://dx.doi.org/10.18632/oncotarget.9733