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Targeting FOSB with a cationic antimicrobial peptide, TP4, for treatment of triple-negative breast cancer

Triple-negative breast cancer (TNBC) currently lacks a suitable therapeutic candidate and is thus difficult to treat. Here, we report that a cationic antimicrobial peptide (CAP), tilapia piscidin 4 (TP4), which was derived from Nile tilapia (Oreochromis niloticus), is selectively toxic to TNBC. TP4...

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Detalles Bibliográficos
Autores principales: Ting, Chen-Hung, Chen, Yi-Chun, Wu, Chang-Jer, Chen, Jyh-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130011/
https://www.ncbi.nlm.nih.gov/pubmed/27248170
http://dx.doi.org/10.18632/oncotarget.9612