Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics

Phenotype-guided re-profiling of approved drug molecules presents an accelerated route to developing anticancer therapeutics by bypassing the target-identification bottleneck of target-based approaches and by sampling drugs already in the clinic. Further, combinations incorporating targeted therapie...

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Detalles Bibliográficos
Autores principales: del Ama, Laura Fernandez, Jones, Mary, Walker, Paul, Chapman, Anna, Braun, Julia A., Mohr, Jasmine, Hurlstone, Adam F. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130012/
https://www.ncbi.nlm.nih.gov/pubmed/27248171
http://dx.doi.org/10.18632/oncotarget.9613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130012/
https://www.ncbi.nlm.nih.gov/pubmed/27248171
http://dx.doi.org/10.18632/oncotarget.9613

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