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Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics
Phenotype-guided re-profiling of approved drug molecules presents an accelerated route to developing anticancer therapeutics by bypassing the target-identification bottleneck of target-based approaches and by sampling drugs already in the clinic. Further, combinations incorporating targeted therapie...
Autores principales: | del Ama, Laura Fernandez, Jones, Mary, Walker, Paul, Chapman, Anna, Braun, Julia A., Mohr, Jasmine, Hurlstone, Adam F. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130012/ https://www.ncbi.nlm.nih.gov/pubmed/27248171 http://dx.doi.org/10.18632/oncotarget.9613 |
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