Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells

High activation of DNA damage response is implicated in cisplatin (CDDP) resistance which presents as a serious obstacle for bladder cancer treatment. Cdc6 plays an important role in the malignant progression of tumor. Here, we reported that Cdc6 expression is up-regulated in bladder cancer tissues...

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Detalles Bibliográficos
Autores principales: Chen, Sansan, Chen, Xinglu, Xie, Gui'e, He, Yue, Yan, Daoyu, Zheng, Dianpeng, Li, Shi, Fu, Xinyang, Li, Yeping, Pang, Xiang, Hu, Zhiming, Li, Hongwei, Tan, Wanlong, Li, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130013/
https://www.ncbi.nlm.nih.gov/pubmed/27246979
http://dx.doi.org/10.18632/oncotarget.9616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130013/
https://www.ncbi.nlm.nih.gov/pubmed/27246979
http://dx.doi.org/10.18632/oncotarget.9616

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