Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway

Sirtuin6 (SIRT6), a member of the sirtuins protein family, plays multiple complex roles in cancer. Here, we report that elevated SIRT6 expression was correlated with clinicopathological parameters such as T and N classification in non-small cell lung cancer (NSCLC) patient tumors. SIRT6 overexpressi...

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Detalles Bibliográficos
Autores principales: Bai, Lihong, Lin, Gengpeng, Sun, Longhua, Liu, Yangli, Huang, Xinyan, Cao, Chuangjie, Guo, Yubiao, Xie, Canmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130014/
https://www.ncbi.nlm.nih.gov/pubmed/27777384
http://dx.doi.org/10.18632/oncotarget.9750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130014/
https://www.ncbi.nlm.nih.gov/pubmed/27777384
http://dx.doi.org/10.18632/oncotarget.9750

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