Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity

Binding of leukemia cells to the bone marrow extracellular matrix (ECM) through integrins might influence drug response and the survival of acute myeloid leukemia (AML). However, the functions of integrin in AML are needed to be clarified. Data from The Cancer Genome Atlas (TCGA) were retrieved and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yi, Hai, Zeng, Dongfeng, Shen, Zhaohua, Liao, Jun, Wang, Xiaoguo, Liu, Yao, Zhang, Xi, Kong, Peiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130015/
https://www.ncbi.nlm.nih.gov/pubmed/27248172
http://dx.doi.org/10.18632/oncotarget.9617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130015/
https://www.ncbi.nlm.nih.gov/pubmed/27248172
http://dx.doi.org/10.18632/oncotarget.9617

Ejemplares similares