Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo

We have recently demonstrated that multi-kinase inhibitors such as sorafenib and pazopanib can suppress the detection of chaperones by in situ immuno-fluorescence, which is further enhanced by phosphodiesterase 5 inhibitors. Sorafenib and pazopanib inhibited the HSP90 ATPase activity with IC50 value...

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Detalles Bibliográficos
Autores principales: Booth, Laurence, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Poklepovic, Andrew, Lebedyeva, Iryna O., Dent, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130016/
https://www.ncbi.nlm.nih.gov/pubmed/27259258
http://dx.doi.org/10.18632/oncotarget.9752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130016/
https://www.ncbi.nlm.nih.gov/pubmed/27259258
http://dx.doi.org/10.18632/oncotarget.9752

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