Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models

Hypoxia is a common feature of solid tumors that activates a plethora of pathways, resulting in proliferation and resistance of cancer cells to radio- and chemotherapy. Pheochromocytomas/paragangliomas (PHEOs/PGLs) with mutations in the gene coding for the subunit B of succinate dehydrogenase (SDHB)...

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Detalles Bibliográficos
Autores principales: Bullova, Petra, Cougnoux, Antony, Abunimer, Luma, Kopacek, Juraj, Pastorekova, Silvia, Pacak, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130026/
https://www.ncbi.nlm.nih.gov/pubmed/27244895
http://dx.doi.org/10.18632/oncotarget.9643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130026/
https://www.ncbi.nlm.nih.gov/pubmed/27244895
http://dx.doi.org/10.18632/oncotarget.9643

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