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Genomic Characterization of Metformin Hepatic Response

Metformin is used as a first-line therapy for type 2 diabetes (T2D) and prescribed for numerous other diseases. However, its mechanism of action in the liver has yet to be characterized in a systematic manner. To comprehensively identify genes and regulatory elements associated with metformin treatm...

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Detalles Bibliográficos
Autores principales: Luizon, Marcelo R., Eckalbar, Walter L., Wang, Yao, Jones, Stacy L., Smith, Robin P., Laurance, Megan, Lin, Lawrence, Gallins, Paul J., Etheridge, Amy S., Wright, Fred, Zhou, Yihui, Molony, Cliona, Innocenti, Federico, Yee, Sook Wah, Giacomini, Kathleen M., Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130177/
https://www.ncbi.nlm.nih.gov/pubmed/27902686
http://dx.doi.org/10.1371/journal.pgen.1006449