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Genomic Characterization of Metformin Hepatic Response
Metformin is used as a first-line therapy for type 2 diabetes (T2D) and prescribed for numerous other diseases. However, its mechanism of action in the liver has yet to be characterized in a systematic manner. To comprehensively identify genes and regulatory elements associated with metformin treatm...
Autores principales: | Luizon, Marcelo R., Eckalbar, Walter L., Wang, Yao, Jones, Stacy L., Smith, Robin P., Laurance, Megan, Lin, Lawrence, Gallins, Paul J., Etheridge, Amy S., Wright, Fred, Zhou, Yihui, Molony, Cliona, Innocenti, Federico, Yee, Sook Wah, Giacomini, Kathleen M., Ahituv, Nadav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130177/ https://www.ncbi.nlm.nih.gov/pubmed/27902686 http://dx.doi.org/10.1371/journal.pgen.1006449 |
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