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Chloroquine Sensitizes Nasopharyngeal Carcinoma Cells but Not Nasoepithelial Cells to Irradiation by Blocking Autophagy

BACKGROUND: Treatment of nasopharyngeal carcinoma requires the application of high dosages of radiation, leading to severe long-term complications in the majority of patients. Sensitizing tumor cells to radiation could be a means to increase the therapeutic window of radiation. Nasopharyngeal carcin...

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Detalles Bibliográficos
Autores principales: Makowska, Anna, Eble, Michael, Prescher, Kirsten, Hoß, Mareike, Kontny, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130215/
https://www.ncbi.nlm.nih.gov/pubmed/27902742
http://dx.doi.org/10.1371/journal.pone.0166766