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Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN

RlmN, a bacterial radical SAM methylating enzyme, has the unusual ability to modify two distinct types of RNA: 23S rRNA and tRNA. In rRNA, RlmN installs a methyl group at the C2 position of A2503 of 23S rRNA, while in tRNA the modification occurs at nucleotide A37, immediately adjacent to the antico...

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Detalles Bibliográficos
Autores principales: Fitzsimmons, Christina M., Fujimori, Danica Galonić
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130265/
https://www.ncbi.nlm.nih.gov/pubmed/27902775
http://dx.doi.org/10.1371/journal.pone.0167298