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Oral Administration of Sitagliptin Activates CREB and Is Neuroprotective in Murine Model of Brain Trauma

Introduction: Traumatic brain injury is a major cause of mortality and morbidity. We have previously shown that the injectable glucagon-like peptide-1 (GLP-1) analog, liraglutide, significantly improved the outcome in mice after severe traumatic brain injury (TBI). In this study we are interested in...

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Detalles Bibliográficos
Autores principales: DellaValle, Brian, Brix, Gitte S., Brock, Birgitte, Gejl, Michael, Rungby, Jørgen, Larsen, Agnete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130988/
https://www.ncbi.nlm.nih.gov/pubmed/27990119
http://dx.doi.org/10.3389/fphar.2016.00450